YAP and TAZ in epithelial stem cells: A sensor for cell polarity, mechanical forces and tissue damage

The YAP/TAZ family of transcriptional co‐activators drives cell proliferation in epithelial tissues and cancers. Yet, how YAP and TAZ are physiologically regulated remains unclear. Here we review recent reports that YAP and TAZ act primarily as sensors of epithelial cell polarity, being inhibited wh...

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Detalles Bibliográficos
Autores principales: Elbediwy, Ahmed, Vincent‐Mistiaen, Zoé I., Thompson, Barry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Prospects & Overviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031209/
https://www.ncbi.nlm.nih.gov/pubmed/27173018
http://dx.doi.org/10.1002/bies.201600037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031209/
https://www.ncbi.nlm.nih.gov/pubmed/27173018
http://dx.doi.org/10.1002/bies.201600037

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