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Testing for the mediating role of endophenotypes using molecular genetic data in a twin study of ADHD traits

Family and twin studies have identified endophenotypes that capture familial and genetic risk in attention‐deficit/hyperactivity disorder (ADHD), but it remains unclear if they lie on the causal pathway. Here, we illustrate a stepwise approach to identifying intermediate phenotypes. First, we use pr...

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Detalles Bibliográficos
Autores principales: Pinto, Rebecca, Asherson, Philip, Ilott, Nicholas, Cheung, Celeste H. M., Kuntsi, Jonna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031223/
https://www.ncbi.nlm.nih.gov/pubmed/27230021
http://dx.doi.org/10.1002/ajmg.b.32463