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Geographic distribution of amino acid mutations in DHFR and DHPS in Plasmodium vivax isolates from Lao PDR, India and Colombia

BACKGROUND: Non-synonymous mutations in dhfr and dhps genes in Plasmodium vivax are associated with sulfadoxine–pyrimethamine (SP) resistance. The present study aimed to assess the prevalence of point mutations in P. vivax dhfr (pvdhfr) and P. vivax dhps (pvdhps) genes in three countries: Lao PDR, I...

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Detalles Bibliográficos
Autores principales: Saralamba, Naowarat, Nakeesathit, Supatchara, Mayxay, Mayfong, Newton, Paul N., Osorio, Lyda, Kim, Jung-Ryong, White, Nicholas J., Day, Nicholas P. J., Dondorp, Arjen M., Imwong, Mallika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031260/
https://www.ncbi.nlm.nih.gov/pubmed/27654047
http://dx.doi.org/10.1186/s12936-016-1543-8