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Analysis of HIV-1 intersubtype recombination breakpoints suggests region with high pairing probability may be a more fundamental factor than sequence similarity affecting HIV-1 recombination

BACKGROUND: With increasing data on HIV-1, a more relevant molecular model describing mechanism details of HIV-1 genetic recombination usually requires upgrades. Currently an incomplete structural understanding of the copy choice mechanism along with several other issues in the field that lack eluci...

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Detalles Bibliográficos
Autores principales: Jia, Lei, Li, Lin, Gui, Tao, Liu, Siyang, Li, Hanping, Han, Jingwan, Guo, Wei, Liu, Yongjian, Li, Jingyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031261/
https://www.ncbi.nlm.nih.gov/pubmed/27655081
http://dx.doi.org/10.1186/s12985-016-0616-1