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Histologic and molecular analysis of patient derived xenografts of high-grade serous ovarian carcinoma
BACKGROUND: Patient derived xenografts (PDX) are generated by transplanting the original patient’s tumor tissue into immune-deficient mice. Unlike xenograft models derived from cell lines, PDX models can better preserve the histopathology from the original patient and molecular pathways. High-grade...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031262/ https://www.ncbi.nlm.nih.gov/pubmed/27655386 http://dx.doi.org/10.1186/s13045-016-0318-6 |