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The E3 ubiquitin ligase Hace1 is required for early embryonic development in Xenopus laevis
BACKGROUND: HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 (HACE1) regulates a wide variety of cellular processes. It has been shown that one of the targets of HACE1 is the GTP-bound form of the small GTPase Rac1. However, the role of HACE1 in early development remains unkno...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031333/ https://www.ncbi.nlm.nih.gov/pubmed/27653971 http://dx.doi.org/10.1186/s12861-016-0132-y |