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The E3 ubiquitin ligase Hace1 is required for early embryonic development in Xenopus laevis

BACKGROUND: HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 (HACE1) regulates a wide variety of cellular processes. It has been shown that one of the targets of HACE1 is the GTP-bound form of the small GTPase Rac1. However, the role of HACE1 in early development remains unkno...

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Detalles Bibliográficos
Autores principales: Iimura, Akira, Yamazaki, Fuhito, Suzuki, Toshiyasu, Endo, Tatsuya, Nishida, Eisuke, Kusakabe, Morioh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031333/
https://www.ncbi.nlm.nih.gov/pubmed/27653971
http://dx.doi.org/10.1186/s12861-016-0132-y