The Anoikis Effector Bit1 Inhibits EMT through Attenuation of TLE1-Mediated Repression of E-Cadherin in Lung Cancer Cells

The mitochondrial Bcl-2 inhibitor of transcription 1 (Bit1) protein is part of an anoikis-regulating pathway that is selectively dependent on integrins. We previously demonstrated that the caspase-independent apoptotic effector Bit1 exerts tumor suppressive function in lung cancer in part by inhibit...

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Detalles Bibliográficos
Autores principales: Yao, Xin, Pham, Tri, Temple, Brandi, Gray, Selena, Cannon, Cornita, Chen, Renwei, Abdel-Mageed, Asim B., Biliran, Hector
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031426/
https://www.ncbi.nlm.nih.gov/pubmed/27655370
http://dx.doi.org/10.1371/journal.pone.0163228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031426/
https://www.ncbi.nlm.nih.gov/pubmed/27655370
http://dx.doi.org/10.1371/journal.pone.0163228

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