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Dscam1 Forms a Complex with Robo1 and the N-Terminal Fragment of Slit to Promote the Growth of Longitudinal Axons

The Slit protein is a major midline repellent for central nervous system (CNS) axons. In vivo, Slit is proteolytically cleaved into N- and C-terminal fragments, but the biological significance of this is unknown. Analysis in the Drosophila ventral nerve cord of a slit allele (slit-UC) that cannot be...

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Detalles Bibliográficos
Autores principales: Alavi, Maryam, Song, Minmin, King, Gracie L. Andrews, Gillis, Taylor, Propst, Robert, Lamanuzzi, Matthew, Bousum, Adam, Miller, Amanda, Allen, Ryan, Kidd, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031454/
https://www.ncbi.nlm.nih.gov/pubmed/27654876
http://dx.doi.org/10.1371/journal.pbio.1002560