A Platform for Interrogating Cancer-Associated p53 Alleles

p53 is the most frequently mutated gene in human cancer. Compelling evidence argues that full transformation involves loss of growth suppression encoded by wild-type p53 together with poorly understood oncogenic activity encoded by missense mutations. Furthermore, distinguishing disease alleles from...

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Detalles Bibliográficos
Autores principales: D’Brot, Alejandro, Kurtz, Paula, Regan, Erin, Jakubowski, Brandon, Abrams, John M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031501/
https://www.ncbi.nlm.nih.gov/pubmed/26996664
http://dx.doi.org/10.1038/onc.2016.48

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031501/
https://www.ncbi.nlm.nih.gov/pubmed/26996664
http://dx.doi.org/10.1038/onc.2016.48

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