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Akt regulates Progesterone Receptor B dependent transcription and angiogenesis in endometrial cancer cells
Progestins have long been used clinically for the treatment of endometrial cancers, however, the response rates to progestin therapy vary and the molecular mechanisms behind progestin insensitivity are poorly understood. We hypothesized that in PTEN mutated endometrial cancers, hyperactive Akt signa...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031502/ https://www.ncbi.nlm.nih.gov/pubmed/26996671 http://dx.doi.org/10.1038/onc.2016.56 |