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Plasma DNA methylation: a potential biomarker for stratification of liver fibrosis in non-alcoholic fatty liver disease

OBJECTIVE: Liver biopsy is currently the most reliable way of evaluating liver fibrosis in patients with non-alcoholic fatty liver disease (NAFLD). Its inherent risks limit its widespread use. Differential liver DNA methylation of peroxisome proliferator-activated receptor gamma (PPARγ) gene promote...

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Detalles Bibliográficos
Autores principales: Hardy, Timothy, Zeybel, Mujdat, Day, Christopher P, Dipper, Christian, Masson, Steven, McPherson, Stuart, Henderson, Elsbeth, Tiniakos, Dina, White, Steve, French, Jeremy, Mann, Derek A, Anstee, Quentin M, Mann, Jelena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031527/
https://www.ncbi.nlm.nih.gov/pubmed/27002005
http://dx.doi.org/10.1136/gutjnl-2016-311526