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Elucidating Combinatorial Chromatin States at Single-Nucleosome Resolution
Chromatin immunoprecipitation followed by sequencing (ChIP-seq) has been instrumental to our current view of chromatin structure and function. It allows genome-wide mapping of histone marks, which demarcate biologically relevant domains. However, ChIP-seq is an ensemble measurement reporting the ave...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031555/ https://www.ncbi.nlm.nih.gov/pubmed/27496019 http://dx.doi.org/10.1016/j.molcel.2016.07.023 |