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Elucidating Combinatorial Chromatin States at Single-Nucleosome Resolution

Chromatin immunoprecipitation followed by sequencing (ChIP-seq) has been instrumental to our current view of chromatin structure and function. It allows genome-wide mapping of histone marks, which demarcate biologically relevant domains. However, ChIP-seq is an ensemble measurement reporting the ave...

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Detalles Bibliográficos
Autores principales: Sadeh, Ronen, Launer-Wachs, Roee, Wandel, Hava, Rahat, Ayelet, Friedman, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031555/
https://www.ncbi.nlm.nih.gov/pubmed/27496019
http://dx.doi.org/10.1016/j.molcel.2016.07.023