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Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose

The arrangement of β cells within islets of Langerhans is critical for insulin release through the generation of rhythmic activity. A privileged role for individual β cells in orchestrating these responses has long been suspected, but not directly demonstrated. We show here that the β cell populatio...

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Detalles Bibliográficos
Autores principales: Johnston, Natalie R., Mitchell, Ryan K., Haythorne, Elizabeth, Pessoa, Maria Paiva, Semplici, Francesca, Ferrer, Jorge, Piemonti, Lorenzo, Marchetti, Piero, Bugliani, Marco, Bosco, Domenico, Berishvili, Ekaterine, Duncanson, Philip, Watkinson, Michael, Broichhagen, Johannes, Trauner, Dirk, Rutter, Guy A., Hodson, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031557/
https://www.ncbi.nlm.nih.gov/pubmed/27452146
http://dx.doi.org/10.1016/j.cmet.2016.06.020