SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling

The linear ubiquitin chain assembly complex (LUBAC) regulates immune signaling, and its function is regulated by the deubiquitinases OTULIN and CYLD, which associate with the catalytic subunit HOIP. However, the mechanism through which CYLD interacts with HOIP is unclear. We here show that CYLD inte...

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Detalles Bibliográficos
Autores principales: Elliott, Paul R., Leske, Derek, Hrdinka, Matous, Bagola, Katrin, Fiil, Berthe K., McLaughlin, Stephen H., Wagstaff, Jane, Volkmar, Norbert, Christianson, John C., Kessler, Benedikt M., Freund, Stefan M.V., Komander, David, Gyrd-Hansen, Mads
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031558/
https://www.ncbi.nlm.nih.gov/pubmed/27591049
http://dx.doi.org/10.1016/j.molcel.2016.08.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031558/
https://www.ncbi.nlm.nih.gov/pubmed/27591049
http://dx.doi.org/10.1016/j.molcel.2016.08.001

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