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The Free Zinc Concentration in the Synaptic Cleft of Artificial Glycinergic Synapses Rises to At least 1 μM

Zn(2+) is concentrated into presynaptic vesicles at many central synapses and is released into the synaptic cleft by nerve terminal stimulation. There is strong evidence that synaptically released Zn(2+) modulates glutamatergic neurotransmission, although there is debate concerning the peak concentr...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Keramidas, Angelo, Lynch, Joseph W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031599/
https://www.ncbi.nlm.nih.gov/pubmed/27713689
http://dx.doi.org/10.3389/fnmol.2016.00088