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ERK5 and Cell Proliferation: Nuclear Localization Is What Matters

ERK5, the last MAP kinase family member discovered, is activated by the upstream kinase MEK5 in response to growth factors and stress stimulation. MEK5-ERK5 pathway has been associated to different cellular processes, playing a crucial role in cell proliferation in normal and cancer cells by mechani...

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Detalles Bibliográficos
Autores principales: Gomez, Nestor, Erazo, Tatiana, Lizcano, Jose M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031611/
https://www.ncbi.nlm.nih.gov/pubmed/27713878
http://dx.doi.org/10.3389/fcell.2016.00105