Synthesis, Biodistribution and In vitro Evaluation of Brain Permeable High Affinity Type 2 Cannabinoid Receptor Agonists [(11)C]MA2 and [(18)F]MA3

The type 2 cannabinoid receptor (CB2) is a member of the endocannabinoid system and is known for its important role in (neuro)inflammation. A PET-imaging agent that allows in vivo visualization of CB2 expression may thus allow quantification of neuroinflammation. In this paper, we report the synthes...

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Detalles Bibliográficos
Autores principales: Ahamed, Muneer, van Veghel, Daisy, Ullmer, Christoph, Van Laere, Koen, Verbruggen, Alfons, Bormans, Guy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031696/
https://www.ncbi.nlm.nih.gov/pubmed/27713686
http://dx.doi.org/10.3389/fnins.2016.00431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031696/
https://www.ncbi.nlm.nih.gov/pubmed/27713686
http://dx.doi.org/10.3389/fnins.2016.00431

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