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Transient Abnormal Myelopoiesis and AML in Down Syndrome: an Update

Children with constitutional trisomy 21 (Down syndrome (DS)) have a unique predisposition to develop myeloid leukaemia of Down syndrome (ML-DS). This disorder is preceded by a transient neonatal preleukaemic syndrome, transient abnormal myelopoiesis (TAM). TAM and ML-DS are caused by co-operation be...

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Detalles Bibliográficos
Autores principales: Bhatnagar, Neha, Nizery, Laure, Tunstall, Oliver, Vyas, Paresh, Roberts, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031718/
https://www.ncbi.nlm.nih.gov/pubmed/27510823
http://dx.doi.org/10.1007/s11899-016-0338-x