Coordinated nuclease activities counteract Ku at single-ended DNA double-strand breaks

Repair of single-ended DNA double-strand breaks (seDSBs) by homologous recombination (HR) requires the generation of a 3′ single-strand DNA overhang by exonuclease activities in a process called DNA resection. However, it is anticipated that the highly abundant DNA end-binding protein Ku sequesters...

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Detalles Bibliográficos
Autores principales: Chanut, Pauline, Britton, Sébastien, Coates, Julia, Jackson, Stephen P., Calsou, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031800/
https://www.ncbi.nlm.nih.gov/pubmed/27641979
http://dx.doi.org/10.1038/ncomms12889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031800/
https://www.ncbi.nlm.nih.gov/pubmed/27641979
http://dx.doi.org/10.1038/ncomms12889

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