Aryl Hydrocarbon Receptor Activation by TCDD Modulates Expression of Extracellular Matrix Remodeling Genes during Experimental Liver Fibrosis

The aryl hydrocarbon receptor (AhR) is a soluble, ligand-activated transcription factor that mediates the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Increasing evidence implicates the AhR in regulating extracellular matrix (ECM) homeostasis. We recently reported that TCDD increased necr...

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Detalles Bibliográficos
Autores principales: Lamb, Cheri L., Cholico, Giovan N., Perkins, Daniel E., Fewkes, Michael T., Oxford, Julia Thom, Lujan, Trevor J., Morrill, Erica E., Mitchell, Kristen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031815/
https://www.ncbi.nlm.nih.gov/pubmed/27672655
http://dx.doi.org/10.1155/2016/5309328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031815/
https://www.ncbi.nlm.nih.gov/pubmed/27672655
http://dx.doi.org/10.1155/2016/5309328

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