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Expression of Phenotypic Astrocyte Marker Is Increased in a Transgenic Mouse Model of Alzheimer's Disease versus Age-Matched Controls: A Presymptomatic Stage Study

Recent mouse studies of the presymptomatic stage of Alzheimer's disease (AD) have suggested that proinflammatory changes, such as glial activation and cytokine induction, may occur already at this early stage through unknown mechanisms. Because TNFα contributes to increased Aβ production from t...

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Detalles Bibliográficos
Autores principales: Doméné, Aurélie, Cavanagh, Chelsea, Page, Guylène, Bodard, Sylvie, Klein, Christophe, Delarasse, Cécile, Chalon, Sylvie, Krantic, Slavica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031839/
https://www.ncbi.nlm.nih.gov/pubmed/27672476
http://dx.doi.org/10.1155/2016/5696241