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Effect of Tongxinluo on Podocyte Apoptosis via Inhibition of Oxidative Stress and P38 Pathway in Diabetic Rats

Diabetic nephropathy (DN) has been the leading cause of end-stage renal disease (ESRD). Podocyte apoptosis is a main mechanism of progression of DN. It has been demonstrated that activated P38 and caspase-3 induced by oxidative stress mainly account for increased podocyte apoptosis and proteinuria i...

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Detalles Bibliográficos
Autores principales: Cui, Fangqiang, Gao, Yanbin, Zhao, Wenjing, Zou, Dawei, Zhu, Zhiyao, Wu, Xiaoming, Tian, Nianxiu, Wang, Xiaolei, Liu, Jing, Tong, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031883/
https://www.ncbi.nlm.nih.gov/pubmed/27672400
http://dx.doi.org/10.1155/2016/5957423