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Renewal of the Holocrine Meibomian Glands by Label-Retaining, Unipotent Epithelial Progenitors

The meibomian and sebaceous glands secrete lipids to prevent desiccation of the ocular surface and skin, respectively. Precisely how these holocrine tissues regenerate is not well understood. To address this, we characterized keratin 5(+) (K5) label-retaining cells (LRCs) and the lineage tracing of...

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Detalles Bibliográficos
Autores principales: Parfitt, Geraint J., Lewis, Phillip N., Young, Robert D., Richardson, Alex, Lyons, J. Guy, Di Girolamo, Nick, Jester, James V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031954/
https://www.ncbi.nlm.nih.gov/pubmed/27523617
http://dx.doi.org/10.1016/j.stemcr.2016.07.010