Energy crisis precedes global metabolic failure in a novel Caenorhabditis elegans Alzheimer Disease model

Alzheimer Disease (AD) is a progressive neurological disorder characterized by the deposition of amyloid beta (Aβ), predominantly the Aβ(1–42) form, in the brain. Mitochondrial dysfunction and impaired energy metabolism are important components of AD pathogenesis. However, the causal and temporal re...

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Detalles Bibliográficos
Autores principales: Fong, Sheng, Teo, Emelyne, Ng, Li Fang, Chen, Ce-Belle, Lakshmanan, Lakshmi Narayanan, Tsoi, Sau Yee, Moore, Philip Keith, Inoue, Takao, Halliwell, Barry, Gruber, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031964/
https://www.ncbi.nlm.nih.gov/pubmed/27653553
http://dx.doi.org/10.1038/srep33781

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031964/
https://www.ncbi.nlm.nih.gov/pubmed/27653553
http://dx.doi.org/10.1038/srep33781

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