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Energy crisis precedes global metabolic failure in a novel Caenorhabditis elegans Alzheimer Disease model
Alzheimer Disease (AD) is a progressive neurological disorder characterized by the deposition of amyloid beta (Aβ), predominantly the Aβ(1–42) form, in the brain. Mitochondrial dysfunction and impaired energy metabolism are important components of AD pathogenesis. However, the causal and temporal re...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031964/ https://www.ncbi.nlm.nih.gov/pubmed/27653553 http://dx.doi.org/10.1038/srep33781 |