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Mesenchymal Stem/Stromal Cells seeded on cartilaginous endplates promote Intervertebral Disc Regeneration through Extracellular Matrix Remodeling

Intervertebral disc (IVD) degeneration is characterized by significant biochemical and histomorphological alterations, such as loss of extracellular matrix (ECM) integrity, by abnormal synthesis of ECM main components, resultant from altered anabolic/catabolic cell activities and cell death. Mesench...

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Detalles Bibliográficos
Autores principales: Pereira, Catarina Leite, Teixeira, Graciosa Q., Ribeiro-Machado, Cláudia, Caldeira, Joana, Costa, Madalena, Figueiredo, Francisco, Fernandes, Rui, Aguiar, Paulo, Grad, Sibylle, Barbosa, Mário A., Gonçalves, Raquel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031983/
https://www.ncbi.nlm.nih.gov/pubmed/27652931
http://dx.doi.org/10.1038/srep33836