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L-MYC Expression Maintains Self-Renewal and Prolongs Multipotency of Primary Human Neural Stem Cells

Pre-clinical studies indicate that neural stem cells (NSCs) can limit or reverse CNS damage through direct cell replacement, promotion of regeneration, or delivery of therapeutic agents. Immortalized NSC lines are in growing demand due to the inherent limitations of adult patient-derived NSCs, inclu...

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Detalles Bibliográficos
Autores principales: Li, Zhongqi, Oganesyan, Diana, Mooney, Rachael, Rong, Xianfang, Christensen, Matthew J., Shahmanyan, David, Perrigue, Patrick M., Benetatos, Joseph, Tsaturyan, Lusine, Aramburo, Soraya, Annala, Alexander J., Lu, Yang, Najbauer, Joseph, Wu, Xiwei, Barish, Michael E., Brody, David L., Aboody, Karen S., Gutova, Margarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031988/
https://www.ncbi.nlm.nih.gov/pubmed/27546534
http://dx.doi.org/10.1016/j.stemcr.2016.07.013