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L-MYC Expression Maintains Self-Renewal and Prolongs Multipotency of Primary Human Neural Stem Cells
Pre-clinical studies indicate that neural stem cells (NSCs) can limit or reverse CNS damage through direct cell replacement, promotion of regeneration, or delivery of therapeutic agents. Immortalized NSC lines are in growing demand due to the inherent limitations of adult patient-derived NSCs, inclu...
Autores principales: | Li, Zhongqi, Oganesyan, Diana, Mooney, Rachael, Rong, Xianfang, Christensen, Matthew J., Shahmanyan, David, Perrigue, Patrick M., Benetatos, Joseph, Tsaturyan, Lusine, Aramburo, Soraya, Annala, Alexander J., Lu, Yang, Najbauer, Joseph, Wu, Xiwei, Barish, Michael E., Brody, David L., Aboody, Karen S., Gutova, Margarita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031988/ https://www.ncbi.nlm.nih.gov/pubmed/27546534 http://dx.doi.org/10.1016/j.stemcr.2016.07.013 |
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