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Combining Yeast Display and Competitive FACS to Select Rare Hapten-Specific Clones from Recombinant Antibody Libraries

[Image: see text] The development of antibodies to low molecular weight haptens remains challenging due to both the low immunogenicity of many haptens and the cross-reactivity of the protein carriers used to generate the immune response. Recombinant antibodies and novel display technologies have gre...

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Detalles Bibliográficos
Autores principales: Sun, Yue, Ban, Bhupal, Bradbury, Andrew, Ansari, G. A. Shakeel, Blake, Diane A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032104/
https://www.ncbi.nlm.nih.gov/pubmed/27571429
http://dx.doi.org/10.1021/acs.analchem.6b02334