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An efficient method for generating a germ cell depleted animal model for studies related to spermatogonial stem cell transplantation

BACKGROUND: Spermatogonial stem cell (SSC) transplantation (SSCT) has become important for conservation of endangered species, transgenesis and for rejuvenating testes which have lost germ cells (Gc) due to gonadotoxic chemotherapy or radiotherapy during the prepubertal phase of life. Creating a ger...

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Detalles Bibliográficos
Autores principales: Ganguli, Nirmalya, Wadhwa, Neerja, Usmani, Abul, Kunj, Neetu, Ganguli, Nilanjana, Sarkar, Rajesh Kumar, Ghorai, Soma M., Majumdar, Subeer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032248/
https://www.ncbi.nlm.nih.gov/pubmed/27659063
http://dx.doi.org/10.1186/s13287-016-0405-1