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Drug Discovery via Human-Derived Stem Cell Organoids

Patient-derived cell lines and animal models have proven invaluable for the understanding of human intestinal diseases and for drug development although both inherently comprise disadvantages and caveats. Many genetically determined intestinal diseases occur in specific tissue microenvironments that...

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Detalles Bibliográficos
Autores principales: Liu, Fangkun, Huang, Jing, Ning, Bo, Liu, Zhixiong, Chen, Shen, Zhao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032635/
https://www.ncbi.nlm.nih.gov/pubmed/27713700
http://dx.doi.org/10.3389/fphar.2016.00334