A miR-335/COX-2/PTEN axis regulates the secretory phenotype of senescent cancer-associated fibroblasts

Senescent cancer-associated fibroblasts (CAF) develop a senescence-associated secretory phenotype (SASP) that is believed to contribute to cancer progression. The mechanisms underlying SASP development are, however, poorly understood. Here we examined the functional role of microRNA in the developme...

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Detalles Bibliográficos
Autores principales: Kabir, Tasnuva D., Leigh, Ross J., Tasena, Hataitip, Mellone, Massimiliano, Coletta, Ricardo D., Parkinson, Eric K., Prime, Stephen S., Thomas, Gareth J., Paterson, Ian C., Zhou, Donghui, McCall, John, Speight, Paul M., Lambert, Daniel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032686/
https://www.ncbi.nlm.nih.gov/pubmed/27385366
http://dx.doi.org/10.18632/aging.100987

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032686/
https://www.ncbi.nlm.nih.gov/pubmed/27385366
http://dx.doi.org/10.18632/aging.100987

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