BMI1 inhibits senescence and enhances the immunomodulatory properties of human mesenchymal stem cells via the direct suppression of MKP-1/DUSP1

For the application of mesenchymal stem cells (MSCs) as clinical therapeutics, the regulation of cellular aging is important to protect hMSCs from an age-associated decline in their function. In this study, we evaluated the effects of hypoxia on cellular senescence and the immunomodulatory abilities...

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Detalles Bibliográficos
Autores principales: Lee, Jin Young, Yu, Kyung-Rok, Kim, Hyung-Sik, Kang, Insung, Kim, Jae-Jun, Lee, Byung-Chul, Choi, Soon Won, Shin, Ji-Hee, Seo, Yoojin, Kang, Kyung-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032689/
https://www.ncbi.nlm.nih.gov/pubmed/27454161
http://dx.doi.org/10.18632/aging.101000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032689/
https://www.ncbi.nlm.nih.gov/pubmed/27454161
http://dx.doi.org/10.18632/aging.101000

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