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Assessment of the contribution of APOE gene variants to metabolic phenotypes associated with familial longevity at middle age

Offspring of long-lived families are characterized by beneficial metabolic phenotypes in glucose and lipid metabolism and low 25-hydroxyvitamin D. Although the genetic basis for human longevity remains largely unclear, the contribution of variation at the APOE locus has been repeatedly demonstrated....

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Detalles Bibliográficos
Autores principales: Noordam, Raymond, Oudt, Charlotte H., Deelen, Joris, Slagboom, P. Eline, Beekman, Marian, van Heemst, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5032696/
https://www.ncbi.nlm.nih.gov/pubmed/27540764
http://dx.doi.org/10.18632/aging.101017