Fully-Automated μMRI Morphometric Phenotyping of the Tc1 Mouse Model of Down Syndrome

We describe a fully automated pipeline for the morphometric phenotyping of mouse brains from μMRI data, and show its application to the Tc1 mouse model of Down syndrome, to identify new morphological phenotypes in the brain of this first transchromosomic animal carrying human chromosome 21. We incor...

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Detalles Bibliográficos
Autores principales: Powell, Nick M., Modat, Marc, Cardoso, M. Jorge, Ma, Da, Holmes, Holly E., Yu, Yichao, O’Callaghan, James, Cleary, Jon O., Sinclair, Ben, Wiseman, Frances K., Tybulewicz, Victor L. J., Fisher, Elizabeth M. C., Lythgoe, Mark F., Ourselin, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033246/
https://www.ncbi.nlm.nih.gov/pubmed/27658297
http://dx.doi.org/10.1371/journal.pone.0162974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033246/
https://www.ncbi.nlm.nih.gov/pubmed/27658297
http://dx.doi.org/10.1371/journal.pone.0162974

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