COMT Val(158)Met Polymorphism Modulates Huntington's Disease Progression

Little is known about the genetic factors modulating the progression of Huntington’s disease (HD). Dopamine levels are affected in HD and modulate executive functions, the main cognitive disorder of HD. We investigated whether the Val(158)Met polymorphism of the catechol-O-methyltransferase (COMT) g...

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Detalles Bibliográficos
Autores principales: de Diego-Balaguer, Ruth, Schramm, Catherine, Rebeix, Isabelle, Dupoux, Emmanuel, Durr, Alexandra, Brice, Alexis, Charles, Perrine, Cleret de Langavant, Laurent, Youssov, Katia, Verny, Christophe, Damotte, Vincent, Azulay, Jean-Philippe, Goizet, Cyril, Simonin, Clémence, Tranchant, Christine, Maison, Patrick, Rialland, Amandine, Schmitz, David, Jacquemot, Charlotte, Fontaine, Bertrand, Bachoud-Lévi, Anne-Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033325/
https://www.ncbi.nlm.nih.gov/pubmed/27657697
http://dx.doi.org/10.1371/journal.pone.0161106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033325/
https://www.ncbi.nlm.nih.gov/pubmed/27657697
http://dx.doi.org/10.1371/journal.pone.0161106

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