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CD4(+) Recent Thymic Emigrants Are Recruited into Granulomas during Leishmania donovani Infection but Have Limited Capacity for Cytokine Production

Recent thymic emigrants (RTEs) represent a source of antigen-naïve T cells that enter the periphery throughout life. However, whether RTEs contribute to the control of chronic parasitic infection and how their potential might be harnessed by therapeutic intervention is currently unclear. Here, we sh...

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Detalles Bibliográficos
Autores principales: Moore, John W. J., Beattie, Lynette, Osman, Mohamed, Owens, Benjamin M. J., Brown, Najmeeyah, Dalton, Jane E., Maroof, Asher, Kaye, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033337/
https://www.ncbi.nlm.nih.gov/pubmed/27658046
http://dx.doi.org/10.1371/journal.pone.0163604