MiR-375 Is Epigenetically Downregulated by HPV-16 E6 Mediated DNMT1 Upregulation and Modulates EMT of Cervical Cancer Cells by Suppressing lncRNA MALAT1

Epigenetic modulation is an important mechanism of miRNA dysregulation in cervical cancer. In this study, we firstly studied how this mechanism contributes to miR-375 downregulation in cervical cancer cells. Then, we further studied the association between miR-375 and MALAT1 (metastasis associated l...

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Detalles Bibliográficos
Autores principales: Liu, Shikai, Song, Lili, Yao, Hairong, Zhang, Liang, Xu, Dongkui, Gao, Fangyuan, Li, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033370/
https://www.ncbi.nlm.nih.gov/pubmed/27658300
http://dx.doi.org/10.1371/journal.pone.0163460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033370/
https://www.ncbi.nlm.nih.gov/pubmed/27658300
http://dx.doi.org/10.1371/journal.pone.0163460

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