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MiR-375 Is Epigenetically Downregulated by HPV-16 E6 Mediated DNMT1 Upregulation and Modulates EMT of Cervical Cancer Cells by Suppressing lncRNA MALAT1
Epigenetic modulation is an important mechanism of miRNA dysregulation in cervical cancer. In this study, we firstly studied how this mechanism contributes to miR-375 downregulation in cervical cancer cells. Then, we further studied the association between miR-375 and MALAT1 (metastasis associated l...
Autores principales: | Liu, Shikai, Song, Lili, Yao, Hairong, Zhang, Liang, Xu, Dongkui, Gao, Fangyuan, Li, Qian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033370/ https://www.ncbi.nlm.nih.gov/pubmed/27658300 http://dx.doi.org/10.1371/journal.pone.0163460 |
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