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Time Course Analysis of Skeletal Muscle Pathology of GDE5 Transgenic Mouse

Glycerophosphodiesterase 5 (GDE5) selectively hydrolyses glycerophosphocholine to choline and is highly expressed in type II fiber-rich skeletal muscles. We have previously generated that a truncated mutant of GDE5 (GDE5dC471) that lacks phosphodiesterase activity and shown that transgenic mice over...

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Detalles Bibliográficos
Autores principales: Hashimoto, Takao, Yang, Bo, Okazaki, Yuri, Yoshizawa, Ikumi, Kajihara, Kaori, Kato, Norihisa, Wada, Masanobu, Yanaka, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033411/
https://www.ncbi.nlm.nih.gov/pubmed/27658304
http://dx.doi.org/10.1371/journal.pone.0163299