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High-Resolution NMR Studies of Human Tissue Factor

In normal hemostasis, the blood clotting cascade is initiated when factor VIIa (fVIIa, other clotting factors are named similarly) binds to the integral membrane protein, human tissue factor (TF). The TF/fVIIa complex in turn activates fX and fIX, eventually concluding with clot formation. Several X...

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Detalles Bibliográficos
Autores principales: Nuzzio, Kristin M., Watt, Eric D., Boettcher, John M., Gajsiewicz, Joshua M., Morrissey, James H., Rienstra, Chad M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033421/
https://www.ncbi.nlm.nih.gov/pubmed/27657719
http://dx.doi.org/10.1371/journal.pone.0163206