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Alternative Splicing of Toll-Like Receptor 9 Transcript in Teleost Fish Grouper Is Regulated by NF-κB Signaling via Phosphorylation of the C-Terminal Domain of the RPB1 Subunit of RNA Polymerase II

Similar to its mammalian counterparts, teleost Toll-like receptor 9 (TLR9) recognizes unmethylated CpG DNA presented in the genome of bacteria or DNA viruses and initiates signaling pathway(s) for immune responses. We have previously shown that the TLR9 pathway in grouper, an economically important...

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Detalles Bibliográficos
Autores principales: Lee, Frank Fang-Yao, Hui, Cho-Fat, Chang, Tien-Hsien, Chiou, Pinwen Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033454/
https://www.ncbi.nlm.nih.gov/pubmed/27658294
http://dx.doi.org/10.1371/journal.pone.0163415