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Dietary Flavones as Dual Inhibitors of DNA Methyltransferases and Histone Methyltransferases

Methylation of DNA and histone proteins are mutually involved in the epigenetic regulation of gene expression mediated by DNA methyltransferases (DNMTs) and histone methyltransferases (HMTs). DNMTs methylate cytosine residues within gene promoters, whereas HMTs catalyze the transfer of methyl groups...

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Detalles Bibliográficos
Autores principales: Kanwal, Rajnee, Datt, Manish, Liu, Xiaoqi, Gupta, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033486/
https://www.ncbi.nlm.nih.gov/pubmed/27658199
http://dx.doi.org/10.1371/journal.pone.0162956