Cargando…
Dietary Flavones as Dual Inhibitors of DNA Methyltransferases and Histone Methyltransferases
Methylation of DNA and histone proteins are mutually involved in the epigenetic regulation of gene expression mediated by DNA methyltransferases (DNMTs) and histone methyltransferases (HMTs). DNMTs methylate cytosine residues within gene promoters, whereas HMTs catalyze the transfer of methyl groups...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033486/ https://www.ncbi.nlm.nih.gov/pubmed/27658199 http://dx.doi.org/10.1371/journal.pone.0162956 |