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The Phospholipase D2 Knock Out Mouse Has Ectopic Purkinje Cells and Suffers from Early Adult-Onset Anosmia

Phospholipase D2 (PLD2) is an enzyme that produces phosphatidic acid (PA), a lipid messenger molecule involved in a number of cellular events including, through its membrane curvature properties, endocytosis. The PLD2 knock out (PLD2KO) mouse has been previously reported to be protected from insult...

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Detalles Bibliográficos
Autores principales: Vermeren, Matthieu M., Zhang, Qifeng, Smethurst, Elizabeth, Segonds-Pichon, Anne, Schrewe, Heinrich, Wakelam, Michael J. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033577/
https://www.ncbi.nlm.nih.gov/pubmed/27658289
http://dx.doi.org/10.1371/journal.pone.0162814