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Phosphate Binding with Sevelamer Preserves Mechanical Competence of Bone Despite Acidosis in Advanced Experimental Renal Insufficiency

INTRODUCTION: Phosphate binding with sevelamer can ameliorate detrimental histomorphometric changes of bone in chronic renal insufficiency (CRI). Here we explored the effects of sevelamer-HCl treatment on bone strength and structure in experimental CRI. METHODS: Forty-eight 8-week-old rats were assi...

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Detalles Bibliográficos
Autores principales: Jokihaara, Jarkko, Pörsti, Ilkka H., Sievänen, Harri, Kööbi, Peeter, Kannus, Pekka, Niemelä, Onni, Turner, Russell T., Iwaniec, Urszula T., Järvinen, Teppo L. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033583/
https://www.ncbi.nlm.nih.gov/pubmed/27658028
http://dx.doi.org/10.1371/journal.pone.0163022