CD82 suppresses CD44 alternative splicing-dependent melanoma metastasis by mediating U2AF2 ubiquitination and degradation

Melanoma is one of the most lethal forms of skin cancer due to its early metastatic spread. The variant form of CD44 (CD44v), a cell surface glycoprotein, is highly expressed on metastatic melanoma. The mechanisms of regulation of CD44 alternative splicing in melanoma and its pathogenic contribution...

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Detalles Bibliográficos
Autores principales: Zhang, Pu, Feng, Shan, Liu, Gentao, Wang, Heyong, Fu, Ailing, Zhu, Huifeng, Ren, Qiao, Wang, Bochu, Xu, Xingran, Bai, Huiyuan, Dong, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033661/
https://www.ncbi.nlm.nih.gov/pubmed/27041584
http://dx.doi.org/10.1038/onc.2016.67

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033661/
https://www.ncbi.nlm.nih.gov/pubmed/27041584
http://dx.doi.org/10.1038/onc.2016.67

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