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The Ca(V)β Subunit Protects the I-II Loop of the Voltage-gated Calcium Channel Ca(V)2.2 from Proteasomal Degradation but Not Oligoubiquitination

Ca(V)β subunits interact with the voltage-gated calcium channel Ca(V)2.2 on a site in the intracellular loop between domains I and II (the I-II loop). This interaction influences the biophysical properties of the channel and leads to an increase in its trafficking to the plasma membrane. We have sho...

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Detalles Bibliográficos
Autores principales: Page, Karen M., Rothwell, Simon W., Dolphin, Annette C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034038/
https://www.ncbi.nlm.nih.gov/pubmed/27489103
http://dx.doi.org/10.1074/jbc.M116.737270