Cargando…
The Ca(V)β Subunit Protects the I-II Loop of the Voltage-gated Calcium Channel Ca(V)2.2 from Proteasomal Degradation but Not Oligoubiquitination
Ca(V)β subunits interact with the voltage-gated calcium channel Ca(V)2.2 on a site in the intracellular loop between domains I and II (the I-II loop). This interaction influences the biophysical properties of the channel and leads to an increase in its trafficking to the plasma membrane. We have sho...
Autores principales: | Page, Karen M., Rothwell, Simon W., Dolphin, Annette C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034038/ https://www.ncbi.nlm.nih.gov/pubmed/27489103 http://dx.doi.org/10.1074/jbc.M116.737270 |
Ejemplares similares
-
β-Subunits Promote the Expression of Ca(V)2.2 Channels by Reducing Their Proteasomal Degradation
por: Waithe, Dominic, et al.
Publicado: (2011) -
Calmodulin regulates Ca(v)3 T-type channels at their gating brake
por: Chemin, Jean, et al.
Publicado: (2017) -
Ca(2+)/Calmodulin-dependent Protein Kinase IIα (αCaMKII) Controls the Activity of the Dopamine Transporter: IMPLICATIONS FOR ANGELMAN SYNDROME
por: Steinkellner, Thomas, et al.
Publicado: (2012) -
Tetraspanin-13 modulates voltage-gated Ca(V)2.2 Ca(2+) channels
por: Mallmann, Robert T., et al.
Publicado: (2013) -
Molecular moieties masking Ca(2+)-dependent facilitation of voltage-gated Ca(v)2.2 Ca(2+) channels
por: Thomas, Jessica R., et al.
Publicado: (2018)