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TRF2 Protein Interacts with Core Histones to Stabilize Chromosome Ends

Mammalian chromosome ends are protected by a specialized nucleoprotein complex called telomeres. Both shelterin, a telomere-specific multi-protein complex, and higher order telomeric chromatin structures combine to stabilize the chromosome ends. Here, we showed that TRF2, a component of shelterin, b...

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Detalles Bibliográficos
Autores principales: Konishi, Akimitsu, Izumi, Takashi, Shimizu, Shigeomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034068/
https://www.ncbi.nlm.nih.gov/pubmed/27514743
http://dx.doi.org/10.1074/jbc.M116.719021