The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening

The ryanodine receptors (RyRs) are intracellular calcium channels responsible for rapid release of Ca(2+) from the sarcoplasmic/endoplasmic reticulum (SR/ER) to the cytoplasm, which is essential for the excitation-contraction (E-C) coupling of cardiac and skeletal muscles. The near-atomic resolution...

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Detalles Bibliográficos
Autores principales: Bai, Xiao-Chen, Yan, Zhen, Wu, Jianping, Li, Zhangqiang, Yan, Nieng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034110/
https://www.ncbi.nlm.nih.gov/pubmed/27468892
http://dx.doi.org/10.1038/cr.2016.89

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034110/
https://www.ncbi.nlm.nih.gov/pubmed/27468892
http://dx.doi.org/10.1038/cr.2016.89

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